Computer-aided classification of lung nodules on computed tomography images via deep learning technique

By K. Hua, Che-Hao Hsu, S. Hidayati, Wen-Huang Cheng, Yu-Jen Chen. OncoTargets and Therapy, 2015

489 citations recorded by the source corpus.

Lung cancer has a poor prognosis when not diagnosed early and unresectable lesions are present. The management of small lung nodules noted on computed tomography scan is controversial due to uncertain tumor characteristics. A conventional computer-aided diagnosis (CAD) scheme requires several image processing and pattern recognition steps to accomplish a quantitative tumor differentiation result. In such an ad hoc image analysis pipeline, every step depends heavily on the performance of the previous step. Accordingly, tuning of classification performance in a conventional CAD scheme is very complicated and arduous. Deep learning techniques, on the other hand, have the intrinsic advantage of an automatic exploitation feature and tuning of performance in a seamless fashion. In this study, we attempted to simplify the image analysis pipeline of conventional CAD with deep learning techniques. Specifically, we introduced models of a deep belief network and a convolutional neural network in the context of nodule classification in computed tomography images. Two baseline methods with feature computing steps were implemented for comparison. The experimental results suggest that deep learning methods could achieve better discriminative results and hold promise in the CAD application domain.

Subfields: Artificial Intelligence, Pulmonary and Respiratory Medicine, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/008749f7ef020053f0ebe661affed0d2d4f7557c

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In Artificial Intelligence

  1. Christopher R'e
  2. Ji Liu
  3. Jared A. Dunnmon
  4. Yutong Xie
  5. Jianpeng Zhang
  6. Yong Xia
  7. D. Feng
  8. Michael J. Fulham

In Pulmonary and Respiratory Medicine

  1. Weidong (Tom) Cai
  2. Daniel L. Rubin
  3. D. Feng
  4. Michael J. Fulham
  5. Matthew P. Lungren
  6. Andy Srinivasan
  7. A. Asuntha

In Radiology, Nuclear Medicine and Imaging

  1. Amitojdeep Singh
  2. June-Goo Lee
  3. Weidong (Tom) Cai
  4. Daniel L. Rubin
  5. D. Feng
  6. Namkug Kim
  7. Michael J. Fulham
  8. Lei Zhao

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