Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
By O. Tam, Alexei Aravin, P. Stein, Angélique Girard, E. Murchison, Sihem Cheloufi, E. Hodges, M. Anger, Ravi Sachidanandam, R. Schultz and 1 more. Nature, 2008
1,121 citations recorded by the source corpus.
Subfields: Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/005c8f04b643f34eb6f6feae9cd9bf6144b55b37
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- David P. Bartel
- John S. Mattick
- Gregory J. Hannon
- Marcel E. Dinger
- David L. Spector
- Eric C. Lai
- Alexei Aravin
- J. Ruby
In Plant Science
- John S. Mattick
- David P. Bartel
- Gregory J. Hannon
- Alexei Aravin
- J. Goodier
- Haig H. Kazazian
- Dubravka Pezic
- Eric C. Lai
Citations in the corpus
- The mammalian ovary from genesis to revelation. (2009, background): “MTB and MTC are almost exclusively regulated by endogenous siRNAs and not piRNAs, indicating that transposon activation in mutant oocytes is secondary to loss of DICER-dependent siRNA biogenesis (627).”
- Long noncoding RNAs: functional surprises from the RNA world. (2009, background): “Several recent reports indicate that RNA transcripts derived from pseudogenes can surprisingly cause mRNAs from the functional protein-coding copy of the gene to be processed to small RNAs (Tam et al. 2008; Watanabe et al. 2008).”
- Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. (2010, background): “…mice, similar precursors are found in the form of hairpin siRNA (hp-siRNA) precursors, but their expression appears to be limited to germline tissues and totipotent ES cells, which lack a robust interferon response to intracellular dsRNA (Babiarz et al. 2008; Tam et al. 2008; Watanabe et al. 2008).”
- The GENCODE pseudogene resource (2012, background): “Recent studies have shown that some pseudogenes can regulate their parent genes’ activity at the transcript level [18, 19, 22, 23, 24].”
- Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges (2012, background): “However, pseudogene-derived small interfering RNAs have been shown to regulate gene expression in mouse oocytes [53].”